US EditionNovel Optogenetics Drug Discovery Screening Platform Identifies Antivirals
A novel optogenetic screening platform enables control over previously intractable biological systems. Using the screening platform, scientists have been able to selectively activate the integrated stress response (ISR). The platform enables a high-throughput screen of 370,830 compounds. In turn, they discovered several ISR-potentiating compounds that sensitize stressed cells to apoptosis without inducing cytotoxicity across diverse cell types a…
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1 Articles
Novel Optogenetics Drug Discovery Screening Platform Identifies Antivirals
A novel optogenetic screening platform enables control over previously intractable biological systems. Using the screening platform, scientists have been able to selectively activate the integrated stress response (ISR). The platform enables a high-throughput screen of 370,830 compounds. In turn, they discovered several ISR-potentiating compounds that sensitize stressed cells to apoptosis without inducing cytotoxicity across diverse cell types a…
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