Smart Microscope Captures Aggregation of Misfolded Proteins
5 Articles
5 Articles
Until today, the skin, brain and all the tissues of the human body were difficult to observe in detail with an optical microscope, because the contrast of the image was hindered by the high density of their structures. The research group of the laboratory of microscopy and molecular spectroscopy at the Istituto italiano di Tecnologia [...]
AI-Driven Microscope Enables Live Imaging of Misfolded Protein Aggregation
Researchers at the Ecole Polytechnique Fédérale de Lausanne (EPFL) have developed a self-driving microscope that can predict the onset of protein aggregation in real time with 91% accuracy. A study published today in Nature Communications showcases how this novel microscopy approach enables live imaging of a process that underlies multiple neurodegenerative conditions such as Huntington’s, Alzheimer’s, or Parkinson’s. “This is the first time we…


An international team led by the University Hospital Hamburg-Eppendorf (UKE) has developed a new method for the high-resolution analysis of tissue samples. With the method "Pathology-Oriented MultiPlexing (PathoPlex)" more than 100 different proteins can be used simultaneously in a...
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