US EditionNew Discoveries Reveal the Impact of Abnormal Chromosome Numbers
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New Discoveries Reveal the Impact of Abnormal Chromosome Numbers
In a groundbreaking study published recently in Nature Communications, researchers from the Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau (RPTU) have unveiled a novel mechanistic link between aneuploidy-induced proteotoxic stress and mitochondrial dysfunction. Their work elucidates how the presence of extra chromosomes in cells disrupts mitochondrial homeostasis by promoting the aggregation of mitochondrial precursor proteins…
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