An Integrative, Multi-Omics Approach Towards the Prioritization of Klebsiella Pneumoniae Drug Targets

An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets

Klebsiella pneumoniae (Kp) is a globally disseminated opportunistic pathogen that can cause life-threatening infections. It has been found as the culprit of many infection outbreaks in hospital environments, being particularly aggressive towards newborns and adults under intensive care. Many Kp strains produce extended-spectrum β-lactamases, enzymes that promote resistance against antibiotics used to fight these infections. The presence of other…

New ASU Study Targets Drug-Resistant Microbes

Antibiotics have long been heralded as one of the greatest achievements in medical science, revolutionizing treatment and saving countless lives worldwide. However, the widespread and often indiscriminate use of these drugs has given rise to an alarming global health crisis: antibiotic resistance. This phenomenon occurs when bacteria evolve mechanisms to evade the lethal effects of antibiotics, birthing formidable “superbugs” that jeopardize hum…