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Mitochondrial abnormalities seen early in many forms of ALS: Study

Summary by ALS News Today
A study found that genetic mutations associated with amyotrophic lateral sclerosis (ALS) lead to problems with the function and transport of mitochondria, cellular structures needed for energy production, early in the disease course, before abnormal protein clumps are formed. “We show that the nerve cells, termed motor neurons, that will eventually die in ALS have problems soon after they are formed,” Eva Hedlund, PhD, co-author of the study and…
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ALS News Today broke the news in on Wednesday, May 28, 2025.
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