FDA OKs trial of pig livers as dialysis-like treatment for liver failure

FDA OKs trial of pig livers as dialysis-like treatment for liver failure

U.S. researchers are about to test if livers from gene-edited pigs could treat people with sudden liver failure — not with a transplant but temporarily attached outside the body.

Pig organ transplant company to enter clinical trials

The local biotech whose technology has already been used for pig-to-human organ transplants is now bringing its first program into the clinic. Cambridge biotech behind pig organ transplants to start human trials

Mirum gets FDA nod for tablet version of liver drug, Livmarli

eGenesis and OrganOx report FDA clearance of IND application for ACLF treatment - BioTuesdays

Closely held eGenesis and OrganOx announced that the FDA has cleared the IND application for EGEN-5784—a human-compatible, genetically engineered porcine liver—designed for use in combination with the OrganOx extracorporeal liver cross-circulation (ELC) system. The therapy targets patients with acute-on-chronic liver failure (ACLF) experiencing decompensated liver function in intensive care. In November 2024, the companies entered into a collabo…

Four Americans with liver failure will be connected extracorporeally to organs from genetically modified animals.

FDA clears clinical trial of gene-edited pig liver used outside of body

The FDA has permitted eGenesis to begin a clinical trial of a dialysis-like system that involves using a gene-edited pig liver outside of the body. It’s the second formal study of a gene-edited pig organ ...