Megabase-Scale Precision Genome Editing Achieved in Eukaryotic Cells

Scientists just cracked the code to editing entire chromosomes flawlessly

A group of Chinese scientists has created powerful new tools that allow them to edit large chunks of DNA with incredible accuracy—and without leaving any trace. Using a mix of advanced protein design, AI, and clever genetic tweaks, they’ve overcome major limitations in older gene editing methods. These tools can flip, remove, or insert massive pieces of genetic code in both plants and animals. To prove it works, they engineered rice that’s resis…

Scientists achieve megabase-scale precision genome editing in eukaryotic cells

A team led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems to achieves multiple types of precise DNA manipulations ranging from kilobase to megabase scale in higher organisms, especially plants.

Programmable Chromosome Engineering systems enable precise DNA manipulations

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

Megabase-scale precision genome editing achieved in eukaryotic cells

A team of Chinese researchers has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

New PCE Systems Enable Precise Genome Engineering Across Kilobase to Megabase Scales

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

Chinese scientists unveil major breakthrough in large-scale DNA editing

Chinese scientists have developed a gene editing technology capable of precisely manipulating large DNA segments ranging from thousands to millions of base pairs in both plant and animal cells, marking a significant advance in the field of life sciences.