US EditionLipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases - Pharma Excipients
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Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases - Pharma Excipients
Abstract Neurodegenerative diseases (NDD) are characterized by the progressive loss of neurons and the impairment of cellular functions. Messenger RNA (mRNA) has emerged as a promising therapy for treating NDD, as it can encode missing or dysfunctional proteins and anti-inflammatory cytokines or neuroprotective proteins to halt the progression of these diseases. However, effective mRNA delivery to the central nervous system (CNS) remains a signi…
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