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Japanese scientists pioneer nonviral gene delivery in primates

Summary by Phys.org
Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a transgene—that is, a gene that has been artificially inserted into an organism—into cynomolgus monkeys, which is a species of primate closely related to humans. The paper is published in the journal Nature Communications.

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Glowing Monkeys? Scientists Rewrite the Rules of Primate Genetic Engineering

Japanese researchers used a nonviral piggyBac system to genetically modify cynomolgus monkeys, enabling more accurate disease models and advancing primate genetic engineering. Genetic engineering in non-human primates has traditionally relied on virus-based methods to deliver genes, which has posed significant limitations. In a recent breakthrough, researchers in Japan successfully introduced a transgene, a gene artificially [...]

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Japanese scientists pioneer nonviral gene delivery in primates

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a transgene—that is, a gene that has been artificially inserted into an organism—into cynomolgus monkeys, which is a species of primate closely related to humans. The paper is published in the journal Nature Communications.

·United Kingdom
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Enhanced Embryo Screening Efficiency in Primate Genetic Modification

Genetic engineering in non-human primates has historically faced limitations due to the reliance on virus-based gene delivery methods.

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GEN - Genetic Engineering and Biotechnology News…GEN - Genetic Engineering and Biotechnology News…

PiggyBac Transposon System Creates Transgenic Cynomolgus Monkeys

Genetic engineering in non-human primates has been challenged by the limitations of virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a transgene into cynomolgus monkeys. “Our research represents a milestone in the field of genetic engineering,” explained Tomoyuki Tsukiyama, PhD, associate professor in developmental engineering, reproductive and stem cell biology at the Institute f…

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Phys.org broke the news in United Kingdom on Tuesday, March 25, 2025.
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