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Top News-Medical.net News

CAR T-Cell Therapy Could Be Made in the Body of Someone with Cancer
Vaccines

CAR T-Cell Therapy Could Be Made in the Body of Someone with Cancer

Coverage: 2 sources
Treating types of cancer with CAR T-cell therapy is expensive and inconvenient, but a streamlined approach that creates the therapy within the body could make the intervention cheaper and easierSee the Story
Cost-Effective Urine Recycling Enabled by a Synthetic Osteoyeast Platform for Production of Hydroxyapatite
Space

Cost-Effective Urine Recycling Enabled by a Synthetic Osteoyeast Platform for Production of Hydroxyapatite

100% Center coverage: 2 sources
Recycling human urine offers a sustainable solution to environmental challenges posed by conventional wastewater treatment. While it is possible to recover nutrients like nitrogen and phosphorus from urine, the low economic value of these products limits large-scale adoption. Here, we show that engineered yeast can convert urine into hydroxyapatite (HAp), a high-value biomaterial widely used in bone and dental applications. Inspired by the biolo…See the Story
New Computational Tool Uncovers Hidden Genetic Mutations in Proteins
Cancer · Toronto

New Computational Tool Uncovers Hidden Genetic Mutations in Proteins

100% Center coverage: 2 sources
Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.See the Story

Collagen and Chitin Amendments Support Soil Microbes to Control Nematode Infections

Collagen and chitin shift soil microbial communities and reduce root-knot nematode infections in tomato plants while improving plant growth and chlorophyll content.Arizona · ArizonaRead Article

Raman Spectroscopy Detects Early Cervical Changes During Pregnancy

Raman spectroscopy detects early biochemical changes in the cervix during pregnancy, revealing increased vascularity and reduced collagen within 6–8 weeks post-conception.Read Article

Do Genetic Variants That Affect DNA Methylation Influence Colorectal Cancer Risk or Outcomes?

The study identifies genetic variants influencing colorectal cancer risk through DNA methylation, suggesting new avenues for targeted screening and prevention.CancerRead Article

New 3D immunohistochemistry method enhances deep tissue imaging

100% Center coverage: 1 sources
Three dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues.ResearchSee the Story

Quantifying Breast Cancer Heterogeneity Through Single-Cell Transcriptomics

Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels.See the Story

Inherited C-Terminal TREX1 Variants Disrupt Homology-Directed Repair to Cause Senescence and DNA Damage Phenotypes in Drosophila, Mice, and Humans

100% Center coverage: 1 sources
Age-related microangiopathy, also known as small vessel disease (SVD), causes damage to the brain, retina, liver, and kidney. Based on the DNA damage theory of aging, we reasoned that genomic instability may underlie an SVD caused by dominant C-terminal variants in TREX1, the most abundant 3′−5′ DNA exonuclease in mammals. C-terminal TREX1 variants cause an adult-onset SVD known as retinal vasculopathy with cerebral leukoencephalopathy (RVCL or …DNASee the Story

Histone Variant H2AZ1 Identified as Key Driver of Stem Cell Aging

Cellular senescence-a state of irreversible growth arrest accompanied by chronic inflammation-is a major contributor to aging and tissue degeneration.Phoenix, Arizona · PhoenixRead Article

Ancient Immune Sensor STING Found to Regulate Gut Microbe Tolerance

Thousands of bacterial and other microbial species live in the human gut, supporting healthy digestion, immunity, metabolism and other functions.SpeciesRead Article

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