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Jacoby Brissett’s Production Raises a Big Question: Is Kyler Murray the Answer for the Cardinals?

Jacoby Brissett completed 27 of 44 passes for 320 yards and two touchdowns despite the Cardinals losing their fourth consecutive game by a combined nine points, coach Jonathan Gannon said.

  • On Sunday, Oct. 12, 2025, Jacoby Brissett served as the Arizona Cardinals' fill-in quarterback in Indianapolis, but Arizona still lost their fourth straight game to the Indianapolis Colts.
  • Kyler Murray remains the team's starter despite missing the game with an ailing foot, Jonathan Gannon said, though Murray’s return this week against the Green Bay Packers is unclear.
  • Brissett delivered a strong offensive showing, producing the Cardinals' best passing output this year while coach Jonathan Gannon praised his poise and command.
  • The Cardinals host the Green Bay Packers on Sunday as they face mounting pressure after losing their last four games by a combined nine points and running out of time to turn the season around.
  • Arizona's defense struggled Sunday, producing just one sack of Colts quarterback Daniel Jones, while Coach Jonathan Gannon offered no updates on injuries to Marvin Harrison Jr., Emari Demercado and Travis Vokolek.
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Jacoby Brissett's production raises a big question: Is Kyler Murray the answer for the Cardinals?

Veteran backup Jacoby Brissett was the fill-in for Cardinals franchise quarterback Kyler Murray against the Indianapolis Colts after Murray’s ailing foot kept him out of action.

·United States
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Fox Sports broke the news in United States on Sunday, October 12, 2025.
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