Early detection of Alzheimer's disease through blood biomarker

From Blood Tests to Brain Scans: How AI is Revolutionizing Alzheimer's Research - USC Viterbi

How advanced technology offers new hope in the fight against a devastating disease.

Neurofilament-light chain quantification by Simoa and Ella in plasma from patients with dementia: a comparative study

Neurofilament light chains (NfL) are neuron-specific cytoskeletal proteins whose plasmatic concentrations have been explored as a clinically useful marker in several types of dementia. Plasma concentrations of NfL are extremely low, and just two assays are commercially available for their study: one based on the SiMoA technology and one based on Ella. We thus studied plasma levels of NfL with both platforms to check the correlation between them …

Taiwan doctors help develop 90% accurate Alzheimer's blood test - Focus Taiwan

Taipei, April 17 (CNA) Taipei Veterans General Hospital (TVGH) on Wednesday announced a research breakthrough that enables a simple blood test to detect individuals at high risk of Alzheimer's disease with around 90 percent accuracy by analyzing specific proteins in blood plasma.

Blood Test Predicts Dementia up to 10 Years in Advance, Study Finds

Blood biomarkers like tau217, NfL, and GFAP may predict dementia up to 10 years early, but aren’t yet reliable for widespread screening, a Karolinska Institutet study finds. A new study published in Nature Medicine has examined the potential of specific biomarkers, tau217, Neurofilament Light (NfL), and Glial Fibrillary Acidic Protein (GFAP), to predict the onset [...]

Early detection of Alzheimer's disease through blood biomarker

Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms.

How do age, sex, hormones and genetics affect dementia biomarkers in the blood?

A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood. The study was published online in Neurology.