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SARS-CoV-2 Structure and Replication Characterized by in Situ Cryo-Electron Tomography

Summary by Nature
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID19 pandemic, is a highly pathogenic β-coronavirus. As other coronaviruses, SARS-CoV-2 is enveloped, replicates in the cytoplasm and assembles at intracellular membranes. Here, we structurally characterize the viral replication compartment and report critical insights into the budding mechanism of the virus, and the structure of extracellular virions clo…

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THIP Media broke the news in on Friday, June 6, 2025.
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