Gene Therapy with VEGF-C Restores Lost Lymphatic Drainage of Cerebrospinal Fluid in Aged Mice

Gene Therapy with VEGF-C Restores Lost Lymphatic Drainage of Cerebrospinal Fluid in Aged Mice

Cerebrospinal fluid is produced constantly, circulates through the brain, and drains into the body. This flow carries metabolic waste from the brain, and researchers are coming to view the age-related impairment of cerebrospinal fluid drainage as an important contribution to loss of cognitive function and the development of neurodegenerative conditions in later life. Several pathways for drainage have been identified, each of which is known to l…