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Enhancing the Photothermal Properties of Indocyanine Green in Melanoma Spheroids via Encapsulation in Span80-Containing Lipid Nanocapsules - Pharma Excipients

Summary by Pharma Excipients
Abstract Indocyanine green (ICG), a well-known photosensitiser, has shown potential in photothermal therapy (PTT) for cancer treatment, but its effectiveness is limited by poor skin penetration and rapid clearance. To address this, lipid nanocapsules (LNCs) were used as nanocarriers to enhance ICG’s cellular uptake and photothermal (PT) performance in melanoma cells. Utilising our recently developed Span 80-modified LNCs (LNC100-S8) with high bi…
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Enhancing the Photothermal Properties of Indocyanine Green in Melanoma Spheroids via Encapsulation in Span80-Containing Lipid Nanocapsules - Pharma Excipients

Abstract Indocyanine green (ICG), a well-known photosensitiser, has shown potential in photothermal therapy (PTT) for cancer treatment, but its effectiveness is limited by poor skin penetration and rapid clearance. To address this, lipid nanocapsules (LNCs) were used as nanocarriers to enhance ICG’s cellular uptake and photothermal (PT) performance in melanoma cells. Utilising our recently developed Span 80-modified LNCs (LNC100-S8) with high bi…

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Pharma Excipients broke the news in on Saturday, March 8, 2025.
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