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Akero says MASH drug reverses liver damage in study, doubling shares

  • Akero Therapeutics' experimental drug Efruxifermin significantly reversed liver damage in a mid-stage study of patients with cirrhosis due to metabolic dysfunction-associated steatohepatitis, according to Akero.
  • The study results exceeded expectations, leading to a more than doubling of Akero's shares and a 50% increase in competitor 89bio's stock.
  • 29% of patients on the highest dose of Efruxifermin showed improvement in liver scarring, compared to only 12% on placebo, as stated by Akero.
  • Analysts described Akero's results as a 'home run' and noted the drug's potential for transformational impact, according to Michael Yee of Jefferies.
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