US EditionTrispecific Antibody Targeting HIV-1 and T Cells Activates and Eliminates Latently-Infected Cells in HIV/SHIV Infections
- On Tuesday, the Democratic Republic of the Congo launched a five-year initiative to eliminate pediatric AIDS by 2030, hailed as “a beacon of hope” by the UN at a Lualaba conference.
- The DRC's new initiative aims to eliminate pediatric AIDS by 2030, addressing the treatment gap where only 44% of HIV-positive children receive care, far behind 91% of adults.
- UNAIDS warns that funding cuts threaten critical HIV supplies, risking shortages of medications, condoms, and essential services like antenatal testing and pediatric treatment within months.
- The DRC's launch of the initiative positions it as a continental leader, with global health watchers hoping it marks a turning point in pediatric HIV elimination in sub-Saharan Africa.
- Aligned with SDG3, the DRC's initiative depends on sustained political, international, and community support to eliminate pediatric AIDS by 2030.
12 Articles
12 Articles
Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections
Agents that can simultaneously activate latent HIV, increase immune activation and enhance the killing of latently-infected cells represent promising approaches for HIV cure. Here, we develop and evaluate a trispecific antibody (Ab), N6/αCD3-αCD28, that targets three independent proteins: (1) the HIV envelope via the broadly reactive CD4-binding site Ab, N6; (2) the T cell antigen CD3; and (3) the co-stimulatory molecule CD28. We find that the t…
Congo-Kinshasa: DR Congo - New Initiative to Eliminate HIV in Children 'A Beacon of Hope'
The Democratic Republic of the Congo (DRC) has launched a bold new national initiative aimed at eliminating AIDS among children by 2030 - a move hailed by the United Nations as "a beacon of hope" amid growing global funding constraints.
Stepping up HIV fight
The recent news of Gilead Sciences' groundbreaking new HIV preventative drug, Lenacapavir, offers a beacon of hope in the fight against HIV. With a remarkable 96% efficacy in reducing HIV infection and the convenience of only two injections per year, Lenacapavir holds the potential to be a true game-changer in the global effort to halt the transmission of HIV.
New infections 67% young men 89% foreigners 27% The number of new HIV infections reported to the domestic quarantine authorities last year was 900, down about 3% from the previous year. HIV progresses after infection.
PNG HIV Infection Rate on the Rise, Health Secretary Warns Citizens to Take Responsibility
The prevalence rate of HIV in Papua New Guinea has risen to alarming levels, with health authorities urging citizens to take personal responsibility to curb the spread of the disease. Acting Health Secretary Ken Wai issued the warning while revealing a concerning upward trend in daily infections.“Globally, new HIV infections have declined by 39 per cent since 2010. In the country however, infections have increased significantly with about 30 new…
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