US EditionDistinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin
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Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin
Salmonella Dublin is a host-adapted, invasive nontyphoidal Salmonella (iNTS) serovar that causes bloodstream infections in humans and demonstrates increasing prevalence of antimicrobial resistance (AMR). Using a global dataset of 1303 genomes, coupled with in vitro assays, we examined the evolutionary, resistance, and virulence characteristics of S. Dublin. Our analysis revealed strong geographical associations between AMR profiles and plasmid t…
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