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Christina Applegate Reveals How MS Diagnosis Has "Broken" 14-Year-Old Daughter Sadie

Christina Applegate shared how her MS diagnosis in 2021 has profoundly affected her 14-year-old daughter Sadie, who has taken on caregiving roles amid family challenges during the COVID-19 pandemic.

  • On the Aug. 5 episode, Christina Applegate, 53, said from her Los Angeles hospital bed that her MS battle has "broken" her teenage daughter Sadie.
  • Applegate recalled being diagnosed with multiple sclerosis in 2021 and said it has caused a steady decline in her mobility in recent years, as discussed on the MeSsy podcast.
  • Sadie regularly assists her mother by helping with Applegate's cane during outings and asking her to make meals at home when she struggles with tasks like stairs.
  • Despite emotional strain, Sadie has remained supportive, often attending awards shows and major events with Christina Applegate, who credits her daughter's care with helping her persevere.
  • Earlier this month Applegate was hospitalized with so much pain that had her screaming, and on Aug. 5 she revealed infections in both kidneys after an emergency CT at 2 AM and treatment with antibiotics.
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arcamax.com broke the news in on Thursday, August 28, 2025.
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