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Titans vs Cardinals Predictions as Tennessee Tries to Upset Kyler Murray, Arizona

Arizona seeks to overcome injuries to top running backs and offensive inconsistencies against the NFL's only winless team, the Tennessee Titans, who struggle with a rookie quarterback.

Summary by The Tennessean
Our experts' predictions are in for Tennessee Titans vs. Arizona Cardinals on Sunday. Here's who our experts are picking to win the Week 5 NFL game.
Podcasts & Opinions

6 Articles

Sports IllustratedSports Illustrated
Lean Left

Can Titans Upset Cardinals?

The Arizona Cardinals welcome the Tennessee Titans to State Farm Stadium in Week 5.

·New York, United States
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CBS SportsCBS Sports
Center

Proven NFL model reveals Titans vs. Cardinals picks, score prediction

SportsLine's model has simulated Cardinals vs. Titans 10,000 times and revealed Week 5 NFL picks

·United States
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The TennesseanThe Tennessean
Center

Titans vs Cardinals predictions as Tennessee tries to upset Kyler Murray, Arizona

Our experts' predictions are in for Tennessee Titans vs. Arizona Cardinals on Sunday. Here's who our experts are picking to win the Week 5 NFL game.

·Nashville, United States
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Nashville PostNashville Post
Center

Titans hopeful Spears, Ridley will play Sunday against Arizona

Running back could be activated after missing first four weeks with ankle injury; receiver a question mark

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AZCentralAZCentral
Lean Left

Cardinals-Titans: Can Arizona solve recent woes against NFL's worst team?

The Arizona Cardinals are 2-2, but they've struggled to score. Against the worst team in the NFL, they'll aim to solve those issues and pick up a win.

·Phoenix, United States
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Decatur DailyDecatur Daily

Cards see stacked deck against woeful Titans

GLENDALE, Ariz. — The Arizona Cardinals are struggling a bit these days, losing consecutive games in gut-wrenching fashion on a pair of last-season field goals.

·Decatur, United States
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AZCentral broke the news in Phoenix, United States on Friday, October 3, 2025.
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