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Strategic partnership between Spanios and GlioGuard to accelerate drug treatments for Glioblastoma (GBM)

Summary by Tri-County Times
HOUSTON, April 1, 2025 /PRNewswire/ -- Spanios is pleased to announce strategic partnership with GlioGuard aimed at propelling discovery and validation of groundbreaking therapeutic options for Glioblastoma (GBM).

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Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy

Intratumor spatial heterogeneity facilitates therapeutic resistance in glioblastoma (GBM). Nonetheless, understanding of GBM heterogeneity is largely limited to the surgically resectable tumor core lesion while the seeds for recurrence reside in the unresectable tumor edge. In this study, stratification of GBM to core and edge demonstrates clinically relevant surgical sequelae. We establish regionally derived models of GBM edge and core that ret…

·United Kingdom
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Winona Daily NewsWinona Daily News
+5 Reposted by 5 other sources
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Strategic partnership between Spanios and GlioGuard to accelerate drug treatments for Glioblastoma (GBM)

HOUSTON, April 1, 2025 /PRNewswire/ -- Spanios is pleased to announce strategic partnership with GlioGuard aimed at propelling discovery and validation of groundbreaking therapeutic options for Glioblastoma (GBM).

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jci.orgjci.org

JCI Lipid peroxidation and immune activation: TRAF3’s double-edged strategy against glioblastoma

Glioblastoma (GBM), the most aggressive type of primary brain tumor, continues to defy therapeutic advances with its metabolic adaptability and resistance to treatment. In this issue of the JCI, Zeng et al. delve into a pivotal mechanism underpinning this adaptability. They identified an important role for TNF receptor–associated factor 3 (TRAF3) in regulating lipid metabolism through its interaction with enoyl-CoA hydratase 1 (ECH1). These find…

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Healthcare Business TodayHealthcare Business Today

How Alejandro Betancourt Is Leading The Fight Against Glioblastoma  - Healthcare Business Today

Glioblastoma multiforme (GBM) remains one of medicine’s most formidable challenges. This aggressive form of brain cancer continues to have poor survival rates despite decades of research. However, neurosurgeons like Dr. Alejandro Betancourt are at the forefront of developing and implementing innovative treatment approaches that offer new hope to patients facing this devastating diagnosis. Expert Credentials ... Read more The post How Alejandro B…

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ABC6ABC6

Brown brain tumor specialist discusses deadly cancer glioblastoma

PROVIDENCE, R.I. (WLNE) — Glioblastoma, an aggressive and deadly form of brain cancer, is diagnosed in approximately 12,000 people per year. The survival after diagnosis is usually just over a year. Doctor Clark Chen, director of the Brain Tumor Program at Brown University Health joined ABC6 Anchor Karah Bailey to discuss this disease. Categories: News, Your Health

·Rhode Island, United States
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ABC6 broke the news in Rhode Island, United States on Monday, March 31, 2025.
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