Evidence of a Causal Association Between Cancer and Alzheimer’s Disease: a Mendelian Randomization Analysis
10 Articles
10 Articles
Evidence of a Causal Association Between Cancer and Alzheimer’s Disease: a Mendelian Randomization Analysis
While limited observational evidence suggests that cancer survivors have a decreased risk of developing Alzheimer’s disease (AD), and vice versa, it is not clear whether this relationship is causal. Using a Mendelian randomization approach that provides evidence of causality, we found that genetically predicted lung cancer (OR 0.91, 95% CI 0.84–0.99, p = 0.019), leukemia (OR 0.98, 95% CI 0.96–0.995, p = 0.012), and breast cancer (OR 0.94, 95% CI…


Is Alzheimer's Risk Less in Cancer Survivors?
(MedPage Today) -- Breast cancer survivors had a slightly lower risk of Alzheimer's dementia than cancer-free people, a population-based cohort study in Korea showed. Over a median follow-up of 7 years, breast cancer survivors had an 8% lower...
Alzheimer’s Disease Risk in Breast Cancer Survivors: New Insights
In a counterintuitive twist to longstanding concerns about cognitive health following cancer treatment, a groundbreaking cohort study has revealed that breast cancer survivors may actually enjoy a reduced risk of developing Alzheimer’s dementia compared to individuals without a cancer history. Published in the reputable JAMA Network Open, this research challenges widely held assumptions about the neurotoxic effects of cancer therapies and posits…
#Advancements in Troculeucel Therapy A Potential Breakthrough for Post-Stroke and Alzheimer?s Patients
'Abstract:' NKGen Biotech is at the forefront of developing innovative cellular therapies, including Troculeucel, which shows promise in treating post-stroke and Alzheimer's disease (AD) patients. Recent advancements include the administration of Troculeucel to a stroke patient under an FDA-cleared compassionate use program and positive Phase 1 clinical trial results demonstrating improved cognitive outcomes in moderate Alzheimer's patients. Add…
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