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Ancient DNA reveals pervasive directional selection across West Eurasia

The study analyzed nearly 16,000 ancient genomes and found 479 variants changed after farming began, with selection affecting immunity and body fat.

Summary by Nature
Ancient DNA has transformed our understanding of population history1, but its potential to reveal as much about human evolutionary biology has not been realized because of limited sample sizes and the difficulty of distinguishing sustained rises in allele frequency increasing fitness—directional selection—from shifts due to migrations, population structure, or non-adaptive purifying or stabilizing selection2–7. Here we present a method for detec…

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Nature broke the news in United Kingdom on Wednesday, April 15, 2026.
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