US EditionAlzheimer’s Decline Slows with Just a Few Thousand Steps a Day
Walking 3,000 to 7,500 steps daily slows tau protein buildup and cognitive decline by up to seven years in older adults at risk for Alzheimer's, study finds.
- On Monday, Mass General Brigham researchers published in Nature Medicine that modest daily steps are linked to slower tau buildup and cognitive decline in 296 Harvard Aging Brain Study adults aged 50.
- With serial PET imaging and annual tests, the study traced participants over a median follow-up of nine years using step-counters and wearable pedometers for a one-week baseline, but it cannot prove causation.
- Using step thresholds, researchers observed graded cognitive benefits; low activity group delayed decline by three years, moderate activity group delayed it by seven years, with benefits plateauing above 7,500 steps.
- Researchers say the benefit was concentrated in participants with high beta-amyloid , and the authors of the Nature Medicine paper recommend targeting inactivity in future randomized clinical trials using wearable activity trackers.
- Because mechanisms remain unclear, authors caution about causality as the study found no link between physical activity and beta-amyloid decline, highlighting urgency with nearly 7 million people living with Alzheimer's in the U.S.
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Time Magazine
DNyuzWalking a Little Each Day Can Slow Down Alzheimer’s Disease
Being physically active is good for every part of you—including your brain. The latest research shows that it can help slow the progression of Alzheimer’s disease in people who are at higher risk of developing the neurodegenerative condition. Other recent studies have made this connection between exercise and better cognitive health, and those results suggest that people with Alzheimer’s disease who are more physically active may be able to slow…
Physical activity can delay the onset of symptoms of Alzheimer’s disease in people at risk, according to a study by Nature Medicine this Monday. A team of scientists from Australia, Canada and the United States has followed for 14 years almost 300 people with preclinical Alzheimer’s disease, who had no symptoms of the disease but had a high build-up of Tau and Beta-amyloid proteins in the brain, which made them at risk. Scientists wanted to find…
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der Standard DEAlready 3000 steps a day contribute to the fact that harmful dew proteinklumps do not accumulate so quickly in the brain – which delays the mental breakdown by years
Around 170,000 people in Austria have dementia, experts estimate. A study could now have discovered a new method to combat the disease: those who move enough can prevent dementia in a sustainable way. Movement not only reduces the risk of dementia, but also slows down the course of the disease. This has been shown by a study published in the journal "Nature Medicine". As early as 3000 steps per day, the Alzheimer's typical protein can become slo…
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