US EditionAlzheimer’s Research Uncovers a New Therapeutic Pathway for the Memory-Robbing Malady
Researchers found that a high-fiber diet reduced Alzheimer's-related frailty and identified migrating gut immune cells as a new therapeutic target in a mouse model study.
5 Articles
5 Articles
Alzheimer’s research uncovers a new therapeutic pathway for the memory-robbing malady
The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD) providing a potential new therapeutic pathway for the memory-robbing malady.
Altered gut immune system in Alzheimer's mouse model provides new target for therapeutics
The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD), providing a potential new therapeutic pathway for the memory-robbing malady.
The immune cells of the intestine can travel to the brain, which provides a new therapeutic target against the alzhéimer. The study, carried out with mice, showed that a fiber-rich diet reduced the fragility related to that disease, including tremors.The entry New scientific pathway: mice with alzhéimer see altered their intestinal immune system was first published in Digital Process.
Gut Immune Cells Found Migrating to Alzheimer’s Brain
Researchers have uncovered a surprising link between gut immune cells and the brain in Alzheimer’s disease. In mice, antibody-producing B cells that normally reside in the gut were found migrating into brain border regions, influenced by chemokine signals from inflammatory brain cells.
Gut Immune System Reshaped by Alzheimer’s Disease in Mice
The role of the gut-brain axis in Alzheimer’s disease (AD) has emerged over recent years as a possible target for therapeutics. But the mechanism linking the two remains to be fully elucidated. In particular, the role of the immune system is poorly understood. New research shows that Alzheimer’s disease is associated with altered immune parameters in the colons of the well-studied Alzheimer’s 5XFAD amyloid-β mouse model. The mice co-express five…
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