Alpha-synuclein clumps may form in kidneys before reaching brain

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Alpha-synuclein clumps may form in kidneys before reaching brain

People with chronic kidney disease, a condition characterized by a progressive loss of kidney function, have alpha-synuclein protein deposits in their kidneys, a study in China has found. Alpha-synuclein is a key marker of Parkinson’s disease, suggesting a possible link between kidney function and the neurodegenerative condition. “These findings are in line with previous reports that [chronic kidney disease] is associated with an increased risk …