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49ers' Brock Purdy out for fourth straight game with toe injury

Mac Jones starts his sixth game as Brock Purdy remains sidelined with a toe injury; Jones leads the NFL with 280.8 passing yards per game, coach says recovery is slow.

  • On Sunday, Mac Jones will start at quarterback in Houston, making his sixth start after Brock Purdy was ruled out but will travel with the team.
  • After re-aggravating his right big toe injury in Week 4, Purdy has missed his fourth straight game and six of the past seven weeks, Shanahan said.
  • Mac Jones has gone 4-1 as a starter, triggering a $400,000 incentive, and leads the NFL with 280.8 passing yards per game.
  • For Sunday, the 49ers ruled out Ricky Pearsall, Bryce Huff, Yetur Gross-Matos and Jake Brendel, while Deommodore Lenoir, Luke Gifford and Spencer Burford are questionable with Burford needing activation by Saturday.
  • Coach Kyle Shanahan said Brandon Aiyuk could return to practice as early as next week and `I believe he's getting a lot closer` after his Oct. 20, 2024 ACL and ligament injuries.
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49ers' Brock Purdy out for fourth straight game with toe injury

Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

·United States
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Sportsnet broke the news in Canada on Friday, October 24, 2025.
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