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Mechanism Revealed Behind the Positive Effects of Cold Temperatures on Delaying Aging and Preventing Age-Related Diseases

Summary by Eurek Alert
Scientists at the University of Cologne identify a key metabolic pathway linking cold temperatures to longevity. The metabolite dihydrobiopterin (BH2) and muscle tissue play a central role in the beneficial effects of cold temperatures on longevity and protein homeostasis. This finding could help prevent certain age-related diseases in the future / publication in Nature.

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The cold affects the muscles in a way that leads them to produce a molecule that lengthens life, according to research led by the University of Cologne (Germany) that is presented today in Nature magazine. This molecule, known as BH2, makes cells of other organs keep their proteins in good condition.Keep reading...

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The Secret Behind How Cold Slows Aging Is Unlocked? The Key Lies in a Substance in Muscles. While it is known that the lifespan of some organisms increases in cold environments, it has not been clearly revealed how cold slows down aging. Researchers at the University of Cologne in Germany have found that a specific substance produced in large quantities in muscles when it is cold slows down the aging of other organs.

A slightly reduced body temperature can be life prolonging. Researchers have now discovered an underlying signal path on threadworms.

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조선일보 broke the news on Wednesday, October 21, 2026.
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