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Wegovy-maker Novo faces calls to map out strategy beyond weight-loss drugs

Investors want clearer targets as trial setbacks, patent expiries and rising competition leave the company’s next growth drivers uncertain.

  • Novo faces intense pressure as rival Lilly's Zepbound treatment is expected to outpace Wegovy by more than $7 billion this year, leaving investors demanding clarity on the European firm's roadmap amid semaglutide patent expiries.
  • After trial setbacks including the failure of CagriSema, Novo shares plunged more than 70% from their peak, prompting the company to raise its sales and operating profit growth targets to between zero and minus 6%.
  • Sydbank analyst Soren Lontoft Hansen said it will be a "very tough task" to convince the market of Novo's strength given price pressure and semaglutide patent expiry at the beginning of the next decade.
  • Union Investment portfolio manager Markus Manns argued Novo should diversify into other therapeutic areas, stating, "They should work harder in building a third leg," as internal research alone cannot bridge the revenue gap.
  • Investors point to European rival AstraZeneca, which forecast $80 billion in annual revenue by 2030, as a model, while analysts warn that without acquisitions, Novo lacks power to compete in the $100 billion weight-loss market.
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ts2.tech broke the news on Sunday, September 20, 2026.
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