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Vitamin B2 Pathway Identified as Potential Target for Cancer Therapy
The vitamin B2 (riboflavin) must be absorbed through diet: it can be found in dairy products, eggs, meat, and green vegetables. The body’s metabolism converts vitamin B2 into molecules that protect the cell from oxidative damage. Now, a CRISPR–Cas9 screen has uncovered vitamin B2 as a modulator of ferroptosis sensitivity: it supports the stability of ferroptosis suppressor protein 1 (FSP1) and the recycling of lipid-soluble antioxidants, thereby…
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The human body cannot synthesize vitamin B2 (also known as riboflavin) on its own and must absorb it through diet from foods such as milk, eggs, meat, and green vegetables.
Vitamin B2 Pathway Identified as Potential Target for Cancer Therapy
The vitamin B2 (riboflavin) must be absorbed through diet: it can be found in dairy products, eggs, meat, and green vegetables. The body’s metabolism converts vitamin B2 into molecules that protect the cell from oxidative damage. Now, a CRISPR–Cas9 screen has uncovered vitamin B2 as a modulator of ferroptosis sensitivity: it supports the stability of ferroptosis suppressor protein 1 (FSP1) and the recycling of lipid-soluble antioxidants, thereby…
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