Vasoactive Vasodilators Show Severity-Dependent Effects on the Progression of Systemic Sclerosis-Associated Interstitial Lung Disease

Vasodilators Show Severity-Dependent Effects in SSc-ILD

TOPLINE: Vasoactive vasodilating drugs (VVDs) have differential effects on the progression of systemic sclerosis-associated interstitial lung disease (SSc-ILD), according to a post hoc analysis of prospectively collected data. Prostanoids were associated with protective benefits in patients with mild vasculopathy, while endothelin-receptor antagonists (ERAs) were linked to a lower risk of worsening symptoms in patients with […] The post Vasodila…

Vasoactive Vasodilators Show Severity-Dependent Effects on the Progression of Systemic Sclerosis-Associated Interstitial Lung Disease

Different vasoactive vasodilating drugs were associated with protective effects depending on patients' vasculopathy, but exposure to these drugs did not affect overall survival.