US EditionUsing generative AI, MIT researchers design compounds that can kill drug-resistant bacteria
MIT researchers used AI to design millions of novel compounds, identifying two antibiotics effective against drug-resistant gonorrhoea and MRSA amid a global health crisis causing over one million deaths annually.
- On August 14, 2025, MIT researchers announced two new antibiotics designed by generative AI that target drug-resistant gonorrhoea and MRSA.
- This breakthrough addresses the urgent antimicrobial resistance crisis worsened by decades without new major antibiotic classes, last discovered in the 1980s.
- The AI analysed 36 million chemical compounds to design novel molecules unlike existing drugs, which succeeded in lab and mouse infection tests.
- Professor James Collins said AI can "expand our arsenal" quickly and cheaply, while experts warn substantial safety testing and economic challenges remain.
- The findings signal a possible second golden age of antibiotic discovery but require years of refinement and clinical trials before patient use.
21 Articles
21 Articles
AI creates new antibiotics
Artificial intelligence (AI) has created two potential new antibiotics that could kill drug-resistant superbugs, including gonorrhoea and MRSA, according to researchers at the Massachusetts Institute of Technology (MIT). The study, published August 14 in Cell, revealed that generative AI designed the drugs atom-by-atom before they were tested successfully in laboratory settings and on infected… Source
AI used to design antibiotics that can combat drug-resistant superbugs gonorrhoea and MRSA
Antibiotics are used to kill bacteria, but some infections have become resistant to drugs. It is estimated drug-resistant bacterial infections cause nearly 5 million deaths per year worldwide.
AI-generated antibiotics have 'enormous potential' to combat superbugs if rolled out
Scientists at the Massachusetts Institute of Technology have used artificial intelligence to develop two promising antibiotics capable of combating drug-resistant strains of gonorrhoea and MRSA.The breakthrough research, published in the journal Cell, marks a significant advance in addressing antibiotic-resistant – or superbug – infections, which claim over one million lives annually.The innovative compounds were constructed atom-by-atom through…
Artificial intelligence (AI) continues to mark milestones in the field of science. Researchers at the Massachusetts Institute of Technology (MIT) have designed, through generative algorithms, new antibiotics that can be used to fight two difficult-to-treat infections: gonorrhea (Neisseria gonorrhoeae) and SAMR (Staphylococcus aureus). Both are resistant to multiple drugs.The finding, published on Cell this Thursday, opens the door to a new era i…
Using generative AI, researchers design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, MIT researchers designed novel antibiotics that can combat a drug-resistant form of Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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