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A Systematic Review of Psychosocial Functioning Changes After Gender-Affirming Hormone Therapy Among Transgender People

Summary by Nature
This systematic review assessed the state and quality of evidence for effects of gender-affirming hormone therapy on psychosocial functioning. Forty-six relevant journal articles (six qualitative, 21 cross-sectional, 19 prospective cohort) were identified. Gender-affirming hormone therapy was consistently found to reduce depressive symptoms and psychological distress. Evidence for quality of life was inconsistent, with some trends suggesting imp…

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Le·gal In·sur·rec·tion broke the news in on Wednesday, June 4, 2025.
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