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US Department of Energy forms $1 billion supercomputer and AI partnership with AMD

  • On Oct 27, the U.S. Department of Energy announced a $1 billion partnership with Advanced Micro Devices to build two supercomputers tackling cancer treatments and national security, Energy Secretary Chris Wright and AMD Chief Executive Lisa Su told Reuters.
  • Officials said the deal aims to maintain U.S. leadership in AI and diversify technology beyond Nvidia Corp., supporting complex experiments that require enormous computing capacity.
  • Engineers will base Lux on AMD's MI355X accelerators and CPUs, coming online within six months, while Discovery will use AMD's MI430 series; both systems are co-developed by ORNL, HPE, OCI, and AMD.
  • Energy Secretary Chris Wright said the systems would "supercharge" advances in nuclear power, fusion, and drug discovery, and "My hope is in the next five or eight years, we will turn most cancers, many of which today are ultimate death sentences, into manageable conditions," Wright said.
  • Industry observers say the pact validates AMD's AI strategy and could catalyse investments in hybrid AI-supercomputing platforms, but supply chain and integration talent risks have delayed past DOE timelines.
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Proactiveinvestors NA broke the news in on Monday, October 27, 2025.
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