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LSU vs. Clemson Picks, Odds: Proven Model Reveals Free Week 1 College Football Predictions, Bets for Saturday

LSU honors Hurricane Katrina's 20th anniversary with a helmet tribute as top quarterbacks Cade Klubnik and Garrett Nussmeier lead a high-stakes season opener under coaches Kelly and Swinney.

  • On August 29, 2025, Baton Rouge Metropolitan Airport hosted its second Season Kickoff Tailgate Party to send LSU fans off to the season opener against Clemson.
  • The event preceded LSU's road game at Clemson's Memorial Stadium, where both schools claim the nickname Death Valley despite different origins.
  • The tailgate featured local vendors, LSU cheerleaders, therapy dog Malarkey, and announced new nonstop flights planned to transport fans to several key away matchups such as those against Vanderbilt, Alabama, and Oklahoma.
  • Clemson opened as a 4-point favorite with-185 moneyline odds and leads the series 3-1, while LSU faces challenges on offense due to the loss of four key offensive linemen and ongoing difficulties in its running game.
  • The primetime game scheduled for August 30, 2025, features two top-10 teams and honors 20 years since Hurricane Katrina with LSU wearing a purple helmet sticker tribute.
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On3 broke the news in on Friday, August 29, 2025.
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