Key Alzheimer's Protein Found at Astonishingly High Levels in Healthy Newborns

Key Alzheimer's protein found at astonishingly high levels in healthy newborns

A protein long blamed for the brain damage seen in Alzheimer’s disease has now been found in astonishingly high levels in healthy newborn babies, challenging decades of medical dogma. The discovery could transform our understanding of both brain development and Alzheimer’s disease itself. The protein, called p-tau217, has been viewed as a hallmark of neurodegeneration – yet a new study reveals it’s even more abundant in the brains of healthy inf…

Did we get Alzheimer’s wrong? New research shows the highest tau protein levels in babies

Alzheimer's disease is marked by the buildup of tau protein levels in the body. But is that the causative agent of the disease or only a result of disease progression? Alzheimer's is the most common form of dementia. For years, scientists have blamed the buildup of p-tau217 protein in the brain for neurodegeneration leading to Alzheimer’s disease. Now, researchers have found that the protein levels are even higher in newborn babies, challenging …

Tau pathology in the brainstem monoaminergic neurons reflect resilience to Alzheimer’s disease pathology in the Nun Study cases

The presence of amyloid and tau pathologies are the pathological hallmarks of Alzheimer’s disease (AD). However, presence of non-demented individuals with sufficient AD pathology (NDAP) indicate that AD-linked pathology does not always lead to dementia. Current view is that NDAP cases re...