US EditionTailored Vitamin D3 Supplementation Lowers Risk of Heart Attack Recurrence
A clinical trial with 630 heart attack patients showed that adjusting vitamin D3 doses to maintain optimal blood levels halved the risk of a second heart attack.
- On Nov. 9, Intermountain Health researchers presented TARGET-D trial results showing targeted vitamin D3 dosing cut the risk of a second heart attack in half.
- Faced with failed uniform-dose trials, researchers noted observational studies linked low vitamin D to worse cardiovascular outcomes but previous clinical trials showed no risk reduction.
- The TARGET-D trial enrolled 630 Intermountain Health patients, set a target level of 40 ng/mL with an average baseline level of 27 ng/mL, and gave nearly 60% a 5,000 IU starting dose.
- Dr. Heidi May highlighted safety and results, stating `We observed no adverse outcomes when giving patients higher doses of vitamin D3 supplementation, and to significantly reduce the risk of another heart attack, which are exciting results`, with follow-up heart attack rates of 3.8% versus 7.9% in the control group, but no difference in overall MACE.
- Researchers will pursue a larger trial to validate the results, aiming to confirm and expand findings that could integrate vitamin D3 management into secondary prevention strategies for heart disease and advance precision cardiovascular medicine.
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Science Daily
One News PageVitamin D3 breakthrough halves risk of second heart attack
Intermountain Health researchers discovered that customizing vitamin D3 doses for heart attack survivors slashed their risk of another heart attack by 50%. The strategy involved frequent monitoring and dose adjustments to reach ideal vitamin D levels. Traditional studies didn’t track blood levels, missing this critical link.
Tailored vitamin D3 supplementation lowers risk of heart attack recurrence
A tailored approach of vitamin D3 supplementation in patients who have suffered a heart attack significantly reduces their risk of a second heart attack, a new study from heart researchers at Intermountain Health in Salt Lake City finds.
Targeted vitamin D3 supplementation cuts risk of second heart attack in half, study finds
A tailored approach of vitamin D3 supplementation in patients who have suffered a heart attack significantly reduces their risk of a second heart attack, a new study from heart researchers at Intermountain Health in Salt Lake City finds.
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