US EditionTANGO2 Loss Causes Desminopathy by Binding Crystallin Alpha B
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TANGO2 Loss Causes Desminopathy by Binding Crystallin Alpha B
In a groundbreaking study published in Nature Communications, researchers have unveiled a critical molecular interaction that may provide new insights into the pathology of desminopathy, a devastating muscle disorder. The team led by Stentenbach, Hughes, and Fagan has identified the protein TANGO2 as a direct binding partner of crystallin alpha B, a small heat shock protein previously known for its chaperone activities in muscle cells. This disc…
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