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ESMO 2025: J&J Eyes Rybrevant Indication Expansion to HNSCC on Phase II Victory - Pharmaceutical Technology

  • Subcutaneous Amivantamab shows a 45 percent overall response rate in patients with recurrent or metastatic head and neck cancer, as reported by Janssen-Cilag International NV.
  • The study found that tumor shrinkage occurred in 82 percent of patients, indicating promising efficacy of Amivantamab, according to the data presented at the ESMO 2025 Congress.
  • Professor Kevin Harrington noted that these findings may improve treatment options for patients facing aggressive head and neck cancer.
  • Janssen-Cilag International NV plans to continue studying Amivantamab in a Phase 3 trial, expanding its evaluation in head and neck cancer treatments.
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LoudounTimes.comLoudounTimes.com
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Subcutaneous amivantamab delivers promising 45 percent overall response rate with median duration of 7.2 months in recurrent or metastatic head and neck cancer

Responses were rapid and durable, and tumor shrinkage was observed in 82 percent of patients

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PR Newswire broke the news in United States on Sunday, October 19, 2025.
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