US EditionStudy shows promise of gene therapy for alcohol use disorder
- Researchers have discovered that a form of gene therapy used to treat Parkinson's disease can significantly reduce alcohol consumption in chronic heavy drinkers by resetting the brain's dopamine reward pathway.
- In a study conducted on nonhuman primates, the gene therapy procedure involved implanting a virus carrying a gene called glial-derived neurotrophic factor into a specific area of the brain. The treated monkeys saw a reduction in drinking by over 90% compared to a control group.
12 Articles
12 Articles
Gene Therapy Rewired Monkey's Brains to Treat Alcohol Use Disorder, Study Finds
Alcohol addiction could become a thing of the past with a new gene therapy that appears to significantly reduce alcohol cravings in monkeys, according to a new study published on Monday in the journal Nature Medicine. The gene therapy was tested on macaque monkeys over 12 months, revealing promising results. Read more...
Form of gene therapy offers hope for severe alcohol addiction, study finds
US research linked to dopamine release finds macaques decreased consumption by up to 90% after treatmentA form of gene therapy that is already being trialled in patients with Parkinson’s disease might provide a one-off treatment for severe alcohol addiction.A study in macaque monkeys that were predisposed to heavy drinking found that it dramatically curbed their alcohol consumption. “Drinking went down to almost zero,” said Prof Kathleen Grant, …
Study shows promise of gene therapy for alcohol use disorder: Already used to treat Parkinson's disease, researchers found surgical treatment dramatically reduced chronic heavy drinking
A form of gene therapy currently used to treat Parkinson's disease may dramatically reduce alcohol use among chronic heavy drinkers, researchers have found.
Researchers found that the effects generated by the new therapeutic approach may prevent the return to alcohol consumption after periods of abstinence. Another step has been taken towards non-drug treatment options for patients with severe alcohol dependence, also called alcohol use disorder. In a new study, published in the journal Nature Medicine, researchers point out that gene therapy may prevent a return to excessive use of alcoholic bevera…
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