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Childhood Asthma Linked to Certain Fatty Foods

The study identifies saturated long-chain fatty acids as triggers for neutrophilic asthma, independent of obesity, suggesting dietary changes could improve management of this severe asthma type in children.

  • Researchers at Children’s Hospital of Philadelphia reported on August 27, 2025, that certain fats in obesity-linked foods cause asthma-like lung inflammation in children.
  • The study began after noticing neutrophilic asthma in non-obese children and found that diets with specific saturated long chain fatty acids trigger this asthma independent of obesity.
  • The research showed that stearic acid, often in animal fat and processed foods, accumulates in lung macrophages and worsens airway inflammation, while oleic acid suppresses inflammation.
  • Before this research, it was widely believed that childhood obesity contributed to this type of asthma; additionally, the study found that inhibiting specific inflammatory proteins helped prevent lung inflammation triggered by stearic acid.
  • These findings, published in Science Translational Medicine, suggest dietary changes and repurposing certain drugs may help prevent and treat this difficult-to-treat asthma subtype in children.
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Fatty Foods Might Contribute To Childhood Asthma

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Medical Xpress broke the news in on Wednesday, August 27, 2025.
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