US EditionStudy finds Ozempic, Wegovy ingredient shows promise for alcohol use disorder in people with obesity
The 6-month trial found lower cravings and less overall drinking, though researchers said the mechanism is still unclear.
- Semaglutide cut heavy drinking days by about 41% in a study of 108 obese adults with alcohol use disorder, researchers at the Mental Health Center Copenhagen reported Thursday.
- The Lancet-published study marks the first randomized controlled trial testing GLP-1 drugs for alcohol use disorder, tracking participants over 26 weeks as they received weekly shots alongside psychotherapy.
- Endocrinologist Dr. Pessah-Polluck stated semaglutide "may be more effective than any of the current FDA-approved medications," while researchers speculated the treatment engages metabolic and reward pathways.
- Study author Dr. Anders Fink-Jensen noted the "strong reduction in the placebo group" likely stemmed from psychotherapy, while the trial included mostly white participants requiring diverse follow-up research.
- Experts warned patients using non-regulated GLP1s "don't exactly know what you are getting," citing risks of "dosing, impurities, additives" that could impede broader clinical adoption.
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A recent study shows that people who received semaglutide drank less. How relevant are these results?
It was revealed by a study on semaglutide done in Denmark and published in The Lancet.The details of the trial.Why it reinforces a possible treatment against addiction.
Controlling diabetes, thinning, protecting the heart ... are increasingly the benefits shown by Ozempic-type drugs. Now a small study, published in 'The Lancet', points out that it could also help reduce alcohol intake. A clinical trial of 108 obese adults seeking treatment for alcohol consumption has shown that a weekly injection of semaglutide (GLP-1 receptor agonist), the active substance of the popular weight loss drug, reduced the days of e…
Active ingredient in Ozempic, Wegovy shows early promise for treating alcohol use disorder among those with obesity: Study
The active ingredient found in popular weight-loss drugs used by millions of people may also help reduce alcohol use in those with obesity, a new study finds.
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