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Researchers Discover Why Living in a Deprived Neighborhood May Raise Dementia Risk

Researchers link neighborhood deprivation to brain vessel damage affecting cognition and lifestyle management, increasing dementia risk in 585 adults aged 40-59, study says.

  • Using PREVENT‑Dementia data, University of Cambridge researchers reported on Nov 5, 2025, that neighborhood deprivation links to brain vessel damage and poorer lifestyle management.
  • Deprived neighbourhoods showed poor housing and environment plus higher crime levels, making it harder for residents to manage modifiable lifestyle risk factors like sleep, exercise, blood pressure, and obesity.
  • Measured outcomes showed the U.S. cohort of 6,781 people had Alzheimer's incidence from 11% to 22% across tracts with least to most disadvantage, with scores declining about 25% faster in the most disadvantaged.
  • Researchers urged policymakers and community leaders to tackle systemic barriers impeding healthy lifestyle changes through targeted campaigns in lower‑income neighbourhoods, improved access to affordable healthcare and healthy food, and safe recreational areas.
  • Importantly, the researchers found links independent of educational attainment, but cautioned the study shows association not causation and urged further research beyond UK and Ireland, noting other cultures and Asian evidence.
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Study confirms living in a poor area ups dementia risk

Researchers found that living in a disadvantaged neighborhood is associated with damage to brain vessels.

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Medical Xpress broke the news in on Wednesday, November 5, 2025.
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