New Mouse Model Sheds Light on Smell Loss and Neural Regeneration

New mouse model sheds light on smell loss and neural regeneration

A new study suggests that stem cells thought to be dormant may offer clues to why our sense of smell declines or is lost.

Researchers develop innovative model to study sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

Stem cells thought to be dormant may offer clues to why sense of smell is lost or declines

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

Researchers Develop Innovative Model To Study Sense of Smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

Dormant Stem Cells May Hold Key to Restoring Sense of Smell

Researchers have created a 3D mouse organoid model to study how neurons in the nose regenerate, revealing that a type of stem cell once considered dormant may be crucial for repairing olfactory tissue. The team found that horizontal basal cells (HBCs), marked by KRT5, actively support new neuron generation alongside globose basal cells (GBCs).