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Stability impact from a titanium dioxide-free film-coated tablet: An analytical investigation into photo-, physical, and chemical stability of compressed tablets made with alternative film-coating materials

Highlights In-depth investigation conducted on titanium dioxide free film coated tablets revealed degradation risks from photostability, physical stability and chemical stability. Calcium carbonate-based film coating was identified as the preferred replacement for titanium dioxide, however risks were identified related to chemical degradation of base-labile APIs. Titanium dioxide was found to be a superior opacifier to all titanium dioxide-free…
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Pharma Excipients broke the news in on Sunday, January 18, 2026.
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