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Spleen-based islet transplantation restores glycemic control in type 1 diabetes without full immunosuppression

Summary by Medical Xpress

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression. Nanoparticle-driven spleen remodeling allowed transplanted mouse, rat, and human islets to restore normal blood sugar in diabetic rodents and cynomolgus macaques.

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Spleen-based islet transplantation restores glycemic control in type 1 diabetes without full immunosuppression

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression. Nanoparticle-driven spleen remodeling allowed transplanted mouse, rat, and human islets to restore normal blood sugar in diabetic rodents and cynomolgus macaques.

1 month ago

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Medical Xpress broke the news in 1 month ago on Monday, May 26, 2025.

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