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Spatial Transcriptomic Analysis Highlights Genetic Adaptability of Glioblastoma

Summary by Inside Precision Medicine
Researchers have used spatial transcriptomics to identify subpopulations of glioblastomas that carry specific genetic alterations in different regions of the tumor, including in extrachromosomal DNA (ecDNA), which may contribute to the tumor’s ability to adapt and become more aggressive. “Our study offers new insights into the interplay between different ecDNA,” said David Craig, PhD, professor and chair of the Department of Integrative Translat…
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Inside Precision Medicine broke the news in on Wednesday, June 18, 2025.
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