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Gut Bacteria Found to Make Serotonin and Boost Intestinal Motility

Researchers found two gut bacteria species that produce serotonin linked to IBS symptoms and observed lower levels of one bacterium in IBS patients, offering new treatment possibilities.

Summary by News Medical
Researchers have identified Limosilactobacillus mucosae and Ligilactobacillus ruminis as human gut bacteria capable of producing serotonin by decarboxylating 5-hydroxytryptophan (5-HTP). Their activity enhances intestinal motility and enteric nerve density, linking microbial serotonin synthesis to gut function and potential IBS mechanisms.

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Medical Xpress broke the news in on Monday, October 20, 2025.
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