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Semaglutide extends lifespan and slows physiological aging in healthy mice

The drug improved muscle and memory measures and added nearly 100 days to median lifespan in treated animals, researchers said.

Summary by News Medical
A National Institutes of Health (NIH)-funded study has shown that the GLP-1 drug semaglutide extended lifespan in older, healthy mice by tempering the detrimental effects of aging.

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Subjecting to a strict caloric restriction, either by reducing food intake or by subjecting to intermittent fasting, is one of the keys that often handle those who investigate aging to delay the biological clock and ultimately extend life expectancy. However, transferring this Spartan rigor to humans is not easy, because for many patients living in hunger is not an attractive recipe, much less in the long term. An alternative could be in the sam…

·Madrid, Spain
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Researchers think that the anti-ageing effect also occurs in people, but warn that there is a lack of studies to prove it.

·Barcelona, Spain
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Wigobi Ingredient Extends Lifespan of Female Mice by 12%: International Joint Research Team Including UC Berkeley Alleviates Cellular Aging and Increases Nerve Cell Production. Animal experiment results indicate that semaglutide, the active ingredient in the obesity treatment Wigobi and the diabetes treatment Ozempic, goes beyond simple weight loss effects to slow aging and extend lifespan, according to international academic research.

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Nature broke the news in London, United Kingdom on Wednesday, September 2, 2026.
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