Scientists reveal atypical depression is a distinct biological subtype linked to antidepressant resistance

Scientists reveal atypical depression is a distinct biological subtype linked to antidepressant resistance

A new genetic and clinical analysis suggests that atypical depression represents a distinct biological subtype of the disorder with specific implications for treatment. The study found that individuals with this form of depression possess unique genetic risk profiles, experience different physical symptoms, and tend to respond less favorably to standard antidepressant medications. These findings were published in Biological Psychiatry. Depressio…